Important Dates

Abstract Submission Deadline

July 20, 2019
August 8, 2019

Conference Date

November 11-14, 2019

Contact Us
Address: Wuhan National Laboratory for Optoelectronics, 1037 Luoyu Road, Wuhan 430074, P. R. China
Tel/Fax: +86-27-87793065
E-mail: poem@mail.hust.edu.cn


History
 

Plenary Speakers

DATE: 7/18/2019

Providing 3D for Super-Resolution Microscopy

and Single-Particle Tracking in Cells with Single Molecules
William E. Moerner
Stanford University, USA
ABSTRACT: Super-resolution microscopy has opened up a new frontier in which biological structures and behavior can be observed in fixed and live cells with resolutions down to 20-40 nm and below.  Examples range from protein superstructures in bacteria to bands in axons to details of the shapes of amyloid fibrils and much more.  Current methods development research addresses ways to extract more information from each single molecule such as 3D position and orientation, and to assure not only precision, but also accuracy. Still, it is worth noting that in spite of all the interest in super-resolution microscopy of extended structures, even in the “conventional” single-molecule tracking regime where the motions of individual biomolecules are recorded in cellular environments, much can be learned. Combining super-resolution imaging of a static structure with 3D tracking of other biomolecules provides a powerful view of cellular dynamics.
 
BIOGRAPHY: W. E. (William Esco) Moerner, the Harry S. Mosher Professor of Chemistry and Professor by courtesy of Applied Physics, has conducted research in physical chemistry, biophysics, and the optical properties of single molecules, and is actively involved in the development of 2D and 3D super-resolution imaging for cell biology. Imaging studies include protein superstructures in bacteria, structure of proteins in cells, studies of chromatin organization, and dynamics of regulatory proteins in the primary cilium. Using powerful microscopes optimized for tracking of single objects in cells, the motions of proteins, DNA, and RNA are being measured in three dimensions in real time to understand processing and binding interactions. A related research area concerns precise analysis of photodynamics of single trapped biomolecules in solution, with applications to photosynthesis, protein-protein interactions, and transport measurements.

Professor Moerner attended Washington University as a Langsdorf Engineering Fellow, graduating in 1975 with degrees in Physics and Electrical Engineering (both B.S. with top honors), and Mathematics (A.B. summa cum laude). His doctoral research in physics at Cornell University (M.S. 1978, Ph.D. 1982) employed tunable infrared lasers to explore infrared vibrational modes of impurities in crystals. In 1982, he moved from New York to San Jose, California to join the IBM Research Division developing spectral holeburning for frequency domain optical storage and photorefractivity for dynamic hologram formation. After 13 years at IBM, Dr. Moerner accepted a position as Distinguished Professor of Physical Chemistry at UC San Diego, where he broadened his research to include biological systems and biophysics. Recruited to the Stanford Chemistry Department faculty in 1997, he served as Chair of the department from 2011 to 2014.

Professor Moerner’s scientific contributions were recognized with the 2014 Nobel Prize in Chemistry "for the development of super-resolved fluorescence microscopy." One method to surpass the optical diffraction limit (PALM/STORM) uses single-molecule imaging combined with a control mechanism to keep the concentration of emitting molecules at a very low level, followed by sequential localization to reconstruct the underlying structure. The fundamentals of this idea came from early work in the Moerner lab: optical detection and imaging of single molecules (1989) combined with blinking and switching at low temperature, as well as the discovery of optical control of single copies of green fluorescent protein at room temperature (1997). Among many other honors and awards, Professor Moerner was elected fellow of the American Physical Society, Optical Society of America, American Association for the Advancement of Science, American Academy of Arts and Sciences; and member of the National Academy of Sciences.
 
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Piezotronics and Piezo-phototronics of the Third Generation Semiconductors
Zhonglin Wang
Beijing Institute of Nanoenergy and Nanosystems, CAS, China
Georgia Institute of Technology, USA
ABSTRACT: Piezoelectricity, a phenomenon known for centuries, is an effect that is about the production of electrical potential in a substance as the pressure on it changes. For wurtzite structures such as ZnO, GaN, InN and ZnS, due to the polarization of ions in a crystal that has non-central symmetry, a piezoelectric potential (piezopotential) is created in the crystal by applying a stress. The effect of piezopotential to the transport behavior of charge carriers is significant due to their multiple functionalities of piezoelectricity, semiconductor and photon excitation. By utilizing the advantages offered by these properties, a few new fields have been created. Electronics fabricated by using inner-crystal piezopotential as a “gate” voltage to tune/control the charge transport behavior is named piezotronics, with applications in strain/force/pressure triggered/controlled electronic devices, sensors and logic units. This effect was also extended to 2D materials such as MoS2. The objective of this talk is to introduce the fundamentals of piezotronics and their application for robotics and human-machine interfacing.
 
BIOGRAPHY: Dr. Zhong Lin (ZL) Wang is the Hightower Chair in Materials Science and Engineering and Regents' Professor at Georgia Tech,and Founding Director and Chief Scientist at Beijing Institute of Nanoenergy and Nanosystems. Dr. Wang pioneered the nanogenerators from fundamental principle to technological applications. His research on self-powered nanosystems has inspired the worldwide effort in academia and industry for studying energy for micro-nano-systems. He coined and pioneered the fields of piezotronics and piezo-phototronics for the third generation semiconductors. Wang is ranked No. 1 in Google Scholar public profiles in Nanotechnology & Nanoscience both in total citations and h-index impacts: http://www.webometrics.info/en/node/198. His google scholar citation is over 200,000 with an h-index of over 225.
0Dr. Wang has received the Albert Einstein World Award of Science (2019); Diels-Planck lecture award (2019); ENI award in Energy Frontiers (2018); Global Nanoenergy Prize, The NANOSMAT Society, UK (2017); Distinguished Research Award, Pan Wen Yuan foundation (2017); Distinguished Scientist Award from (US) Southeastern Universities Research Association (2016); Thomas Router Citation Laureate in Physics (2015); World Technology Award (Materials) (2014); Distinguished Professor Award (Highest faculty honor at Georgia Tech) (2014); NANOSMAT prize (United Kingdom) (2014); The James C. McGroddy Prize in New Materials from American Physical Society (2014); MRS Medal from Materials Research Soci. (2011). Dr. Wang was elected as a foreign member of the Chinese Academy of Sciences in 2009, member of European Academy of Sciences in 2002, academician of Academia of Sinica 2018, Foreign member of Korean Academy of Science and Technology 2019, International fellow of Canadian Academy of Engineering 2019; fellow of American Physical Society in 2005, fellow of AAAS in 2006, fellow of Materials Research Society in 2008, fellow of Microscopy Society of America in 2010, fellow of the World Innovation Foundation in 2002, fellow of Royal Society of Chemistry, and fellow of World Technology Network 2014. Dr. Wang is the founding editor and chief editor of an international journal Nano Energy, which now has an impact factor of 15. Details can be found at: http://www.nanoscience.gatech.edu
 
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A Revolution in Miniature Optical Clocks and Frequency Synthesizers
Kerry J. Vahala
California Institute of Technology, USA
ABSTRACT: Over the last few decades, the distinctly different strengths of photonics and electronics have been harnessed in entirely new ways by the optical frequency comb. As a bi-directional and coherent link, it has enabled sharing of performance attributes previously unique to these two worlds. The end result has been transformative for time keeping, frequency metrology, precision spectroscopy, microwave-generation, ranging and other technologies. Over the same span of time, resonantly enhanced parametric gain and four-wave mixing in high-Q microcavities were observed. And by cascading the four-wave mixing process to many orders a miniature frequency comb or `microcomb’ was demonstrated. Even more recently, the demonstration of coherently-pumped soliton mode locking in fiber resonators and in micro-resonators has been a major advance for these miniature frequency comb devices. As mode-locked optical oscillators, soliton operation provides stable repetition rates and reproducible waveforms, which are essential ingredients in all comb applications. Referred to as both `cavity solitons’ and `dissipative Kerr’ solitons, they have opened new perspectives on optical soliton physics and integrated comb systems on-a-chip. The latter includes system-level demonstration of massively-parallel WDM channel generation for coherent communication, C-band optical fre